Common Stock Valuation Ratios (Price Multiples)
Valuation ratios measure the quantity of an asset or flaw (e.g., earnings) associated with ownership of a specified claim (e.g., a share of ownership of the enterprise).
Current Valuation Ratios
Vertex Pharmaceuticals Inc., current price multiples
| Vertex Pharmaceuticals Inc. | AbbVie Inc. | Amgen Inc. | Bristol-Myers Squibb Co. | Danaher Corp. | Eli Lilly & Co. | Gilead Sciences Inc. | Johnson & Johnson | Merck & Co. Inc. | Pfizer Inc. | Regeneron Pharmaceuticals Inc. | Thermo Fisher Scientific Inc. | Pharmaceuticals, Biotechnology & Life Sciences | Health Care | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data | |||||||||||||||||
| Current share price (P) | $492.69 | ||||||||||||||||
| No. shares of common stock outstanding | 256,789,869 | ||||||||||||||||
| Earnings per share (EPS) | $-2.09 | ||||||||||||||||
| Operating profit per share | $-0.91 | ||||||||||||||||
| Sales per share | $42.91 | ||||||||||||||||
| Book value per share (BVPS) | $63.90 | ||||||||||||||||
| Valuation Ratios (Price Multiples) | |||||||||||||||||
| Price to sales (P/S) | 11.48 | 6.43 | 5.15 | 2.52 | 6.16 | 17.31 | 4.87 | 4.44 | 3.51 | 2.25 | 4.91 | 4.40 | 5.52 | 2.30 | |||
| Price to book value (P/BV) | 7.71 | 109.00 | 28.06 | 7.46 | 2.97 | 54.95 | 7.20 | 5.51 | 4.87 | 1.62 | 2.37 | 3.81 | 6.98 | 5.32 | |||
Based on: 10-K (reporting date: 2024-12-31).
If the company price multiple is lower then the price multiple of benchmark then company stock is relatively undervalued.
Otherwise, if the company price multiple is higher then the price multiple of benchmark then company stock is relatively overvalued.
Historical Valuation Ratios (Summary)
Vertex Pharmaceuticals Inc., historical price multiples
Based on: 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31).
| Valuation ratio | Description | The company |
|---|---|---|
| P/S ratio | An rationale for the P/S ratio is that sales, as the top line in an income statement, are generally less subject to distortion or manipulation than other fundamentals such as EPS or book value. Sales are also more stable than earnings and never negative. | Vertex Pharmaceuticals Inc. P/S ratio increased from 2022 to 2023 but then slightly decreased from 2023 to 2024. |
| P/BV ratio | The P/BV ratio is interpreted as an indicator of market judgment about the relationship between a company required rate of return and its actual rate of return. | Vertex Pharmaceuticals Inc. P/BV ratio increased from 2022 to 2023 and from 2023 to 2024. |
Price to Earnings (P/E)
Vertex Pharmaceuticals Inc., historical P/E calculation, comparison to benchmarks
| Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | ||
|---|---|---|---|---|---|---|
| No. shares of common stock outstanding1 | 256,789,869 | 258,307,816 | 257,091,441 | 254,576,691 | 259,960,062 | |
| Selected Financial Data (US$) | ||||||
| Net income (loss) (in thousands) | (535,600) | 3,619,600) | 3,322,000) | 2,342,100) | 2,711,647) | |
| Earnings per share (EPS)2 | -2.09 | 14.01 | 12.92 | 9.20 | 10.43 | |
| Share price1, 3 | 462.58 | 426.29 | 297.40 | 244.24 | 210.50 | |
| Valuation Ratio | ||||||
| P/E ratio4 | — | 30.42 | 23.02 | 26.55 | 20.18 | |
| Benchmarks | ||||||
| P/E Ratio, Competitors5 | ||||||
| AbbVie Inc. | 79.59 | 63.84 | 22.62 | 22.07 | 40.17 | |
| Amgen Inc. | 38.24 | 23.14 | 19.56 | 21.05 | 18.82 | |
| Bristol-Myers Squibb Co. | — | 12.27 | 23.97 | 20.92 | — | |
| Danaher Corp. | 38.12 | 39.09 | 25.65 | 29.94 | 44.49 | |
| Eli Lilly & Co. | 77.63 | 135.24 | 50.08 | 40.66 | 31.95 | |
| Gilead Sciences Inc. | 296.57 | 16.17 | 22.68 | 12.36 | 641.48 | |
| Johnson & Johnson | 26.92 | 10.73 | 22.97 | 20.93 | 28.92 | |
| Merck & Co. Inc. | 13.49 | 893.99 | 19.21 | 14.78 | 26.72 | |
| Pfizer Inc. | 18.42 | 73.42 | 7.58 | 11.76 | 19.62 | |
| Regeneron Pharmaceuticals Inc. | 17.76 | 25.99 | 19.68 | 8.37 | 15.09 | |
| Thermo Fisher Scientific Inc. | 32.03 | 35.65 | 30.55 | 27.35 | 27.89 | |
| P/E Ratio, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 45.15 | 32.80 | 20.23 | 19.27 | 34.89 | |
| P/E Ratio, Industry | ||||||
| Health Care | 36.74 | 29.04 | 21.06 | 21.09 | 28.93 | |
Based on: 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31).
1 Data adjusted for splits and stock dividends.
2 2024 Calculation
EPS = Net income (loss) ÷ No. shares of common stock outstanding
= -535,600,000 ÷ 256,789,869 = -2.09
3 Closing price as at the filing date of Vertex Pharmaceuticals Inc. Annual Report.
4 2024 Calculation
P/E ratio = Share price ÷ EPS
= 462.58 ÷ -2.09 = —
5 Click competitor name to see calculations.
Price to Operating Profit (P/OP)
Vertex Pharmaceuticals Inc., historical P/OP calculation, comparison to benchmarks
| Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | ||
|---|---|---|---|---|---|---|
| No. shares of common stock outstanding1 | 256,789,869 | 258,307,816 | 257,091,441 | 254,576,691 | 259,960,062 | |
| Selected Financial Data (US$) | ||||||
| Income (loss) from operations (in thousands) | (232,900) | 3,832,000) | 4,307,400) | 2,782,100) | 2,856,290) | |
| Operating profit per share2 | -0.91 | 14.84 | 16.75 | 10.93 | 10.99 | |
| Share price1, 3 | 462.58 | 426.29 | 297.40 | 244.24 | 210.50 | |
| Valuation Ratio | ||||||
| P/OP ratio4 | — | 28.74 | 17.75 | 22.35 | 19.16 | |
| Benchmarks | ||||||
| P/OP Ratio, Competitors5 | ||||||
| AbbVie Inc. | 37.26 | 24.34 | 14.78 | 14.21 | 16.32 | |
| Amgen Inc. | 21.55 | 19.69 | 13.40 | 16.24 | 14.96 | |
| Bristol-Myers Squibb Co. | — | 13.53 | 18.29 | 19.84 | — | |
| Danaher Corp. | 30.56 | 35.64 | 20.97 | 25.14 | 36.91 | |
| Eli Lilly & Co. | 63.73 | 109.75 | 43.88 | 35.70 | 32.66 | |
| Gilead Sciences Inc. | 85.65 | 12.05 | 14.21 | 7.76 | 19.38 | |
| Johnson & Johnson | 18.20 | 17.78 | 17.62 | 18.68 | 21.84 | |
| Merck & Co. Inc. | 11.60 | 138.56 | 15.55 | 15.39 | 23.89 | |
| Pfizer Inc. | 11.92 | 121.63 | 6.64 | 12.74 | 21.12 | |
| Regeneron Pharmaceuticals Inc. | 19.63 | 25.39 | 18.01 | 7.55 | 14.82 | |
| Thermo Fisher Scientific Inc. | 27.65 | 31.16 | 25.30 | 21.07 | 22.81 | |
| P/OP Ratio, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 31.13 | 32.68 | 15.94 | 16.68 | 25.95 | |
| P/OP Ratio, Industry | ||||||
| Health Care | 24.96 | 24.91 | 16.28 | 17.33 | 21.54 | |
Based on: 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31).
1 Data adjusted for splits and stock dividends.
2 2024 Calculation
Operating profit per share = Income (loss) from operations ÷ No. shares of common stock outstanding
= -232,900,000 ÷ 256,789,869 = -0.91
3 Closing price as at the filing date of Vertex Pharmaceuticals Inc. Annual Report.
4 2024 Calculation
P/OP ratio = Share price ÷ Operating profit per share
= 462.58 ÷ -0.91 = —
5 Click competitor name to see calculations.
Price to Sales (P/S)
Vertex Pharmaceuticals Inc., historical P/S calculation, comparison to benchmarks
| Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | ||
|---|---|---|---|---|---|---|
| No. shares of common stock outstanding1 | 256,789,869 | 258,307,816 | 257,091,441 | 254,576,691 | 259,960,062 | |
| Selected Financial Data (US$) | ||||||
| Revenues (in thousands) | 11,020,100) | 9,869,200) | 8,930,700) | 7,574,400) | 6,205,683) | |
| Sales per share2 | 42.91 | 38.21 | 34.74 | 29.75 | 23.87 | |
| Share price1, 3 | 462.58 | 426.29 | 297.40 | 244.24 | 210.50 | |
| Valuation Ratio | ||||||
| P/S ratio4 | 10.78 | 11.16 | 8.56 | 8.21 | 8.82 | |
| Benchmarks | ||||||
| P/S Ratio, Competitors5 | ||||||
| AbbVie Inc. | 6.04 | 5.72 | 4.61 | 4.53 | 4.05 | |
| Amgen Inc. | 4.88 | 5.78 | 5.17 | 5.10 | 5.64 | |
| Bristol-Myers Squibb Co. | 2.36 | 2.19 | 3.29 | 3.16 | 3.16 | |
| Danaher Corp. | 6.23 | 7.76 | 5.79 | 6.37 | 7.01 | |
| Eli Lilly & Co. | 18.25 | 20.77 | 10.96 | 8.01 | 8.06 | |
| Gilead Sciences Inc. | 4.98 | 3.40 | 3.86 | 2.85 | 3.24 | |
| Johnson & Johnson | 4.26 | 4.43 | 4.34 | 4.66 | 5.15 | |
| Merck & Co. Inc. | 3.60 | 5.43 | 4.71 | 3.96 | 3.93 | |
| Pfizer Inc. | 2.32 | 2.61 | 2.35 | 3.15 | 4.42 | |
| Regeneron Pharmaceuticals Inc. | 5.52 | 7.84 | 7.01 | 4.20 | 6.24 | |
| Thermo Fisher Scientific Inc. | 4.73 | 4.99 | 4.73 | 5.39 | 5.52 | |
| P/S Ratio, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 5.55 | 5.89 | 4.56 | 4.50 | 4.90 | |
| P/S Ratio, Industry | ||||||
| Health Care | 2.29 | 2.46 | 2.26 | 2.39 | 2.33 | |
Based on: 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31).
1 Data adjusted for splits and stock dividends.
2 2024 Calculation
Sales per share = Revenues ÷ No. shares of common stock outstanding
= 11,020,100,000 ÷ 256,789,869 = 42.91
3 Closing price as at the filing date of Vertex Pharmaceuticals Inc. Annual Report.
4 2024 Calculation
P/S ratio = Share price ÷ Sales per share
= 462.58 ÷ 42.91 = 10.78
5 Click competitor name to see calculations.
| Valuation ratio | Description | The company |
|---|---|---|
| P/S ratio | An rationale for the P/S ratio is that sales, as the top line in an income statement, are generally less subject to distortion or manipulation than other fundamentals such as EPS or book value. Sales are also more stable than earnings and never negative. | Vertex Pharmaceuticals Inc. P/S ratio increased from 2022 to 2023 but then slightly decreased from 2023 to 2024. |
Price to Book Value (P/BV)
Vertex Pharmaceuticals Inc., historical P/BV calculation, comparison to benchmarks
| Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | ||
|---|---|---|---|---|---|---|
| No. shares of common stock outstanding1 | 256,789,869 | 258,307,816 | 257,091,441 | 254,576,691 | 259,960,062 | |
| Selected Financial Data (US$) | ||||||
| Shareholders’ equity (in thousands) | 16,409,600) | 17,580,400) | 13,912,700) | 10,100,000) | 8,686,815) | |
| Book value per share (BVPS)2 | 63.90 | 68.06 | 54.12 | 39.67 | 33.42 | |
| Share price1, 3 | 462.58 | 426.29 | 297.40 | 244.24 | 210.50 | |
| Valuation Ratio | ||||||
| P/BV ratio4 | 7.24 | 6.26 | 5.50 | 6.16 | 6.30 | |
| Benchmarks | ||||||
| P/BV Ratio, Competitors5 | ||||||
| AbbVie Inc. | 102.40 | 29.97 | 15.52 | 16.53 | 14.18 | |
| Amgen Inc. | 26.61 | 24.94 | 35.01 | 18.51 | 14.53 | |
| Bristol-Myers Squibb Co. | 6.98 | 3.35 | 4.88 | 4.07 | 3.55 | |
| Danaher Corp. | 3.00 | 3.47 | 3.64 | 4.16 | 3.93 | |
| Eli Lilly & Co. | 57.93 | 65.80 | 29.36 | 25.28 | 35.07 | |
| Gilead Sciences Inc. | 7.36 | 4.01 | 4.90 | 3.65 | 4.33 | |
| Johnson & Johnson | 5.30 | 5.48 | 5.37 | 5.90 | 6.72 | |
| Merck & Co. Inc. | 4.99 | 8.68 | 6.07 | 5.05 | 7.46 | |
| Pfizer Inc. | 1.68 | 1.75 | 2.48 | 3.35 | 2.98 | |
| Regeneron Pharmaceuticals Inc. | 2.67 | 3.96 | 3.77 | 3.60 | 4.81 | |
| Thermo Fisher Scientific Inc. | 4.09 | 4.57 | 4.83 | 5.18 | 5.15 | |
| P/BV Ratio, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 7.03 | 6.77 | 5.66 | 5.72 | 5.99 | |
| P/BV Ratio, Industry | ||||||
| Health Care | 5.29 | 5.25 | 4.73 | 4.84 | 4.63 | |
Based on: 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31).
1 Data adjusted for splits and stock dividends.
2 2024 Calculation
BVPS = Shareholders’ equity ÷ No. shares of common stock outstanding
= 16,409,600,000 ÷ 256,789,869 = 63.90
3 Closing price as at the filing date of Vertex Pharmaceuticals Inc. Annual Report.
4 2024 Calculation
P/BV ratio = Share price ÷ BVPS
= 462.58 ÷ 63.90 = 7.24
5 Click competitor name to see calculations.
| Valuation ratio | Description | The company |
|---|---|---|
| P/BV ratio | The P/BV ratio is interpreted as an indicator of market judgment about the relationship between a company required rate of return and its actual rate of return. | Vertex Pharmaceuticals Inc. P/BV ratio increased from 2022 to 2023 and from 2023 to 2024. |