Analysis of Profitability Ratios
Profitability ratios measure the company ability to generate profitable sales from its resources (assets).
Profitability Ratios (Summary)
Cytokinetics Inc., profitability ratios
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31).
| Profitability ratio | Description | The company |
|---|---|---|
| Operating profit margin | A profitability ratio calculated as operating income divided by revenue. | Cytokinetics Inc. operating profit margin ratio deteriorated from 2020 to 2021 and from 2021 to 2022. |
| Net profit margin | An indicator of profitability, calculated as net income divided by revenue. | Cytokinetics Inc. net profit margin ratio deteriorated from 2020 to 2021 and from 2021 to 2022. |
| Profitability ratio | Description | The company |
|---|---|---|
| ROA | A profitability ratio calculated as net income divided by total assets. | Cytokinetics Inc. ROA deteriorated from 2020 to 2021 and from 2021 to 2022. |
Operating Profit Margin
Cytokinetics Inc., operating profit margin calculation, comparison to benchmarks
| Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | ||
|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||
| Operating loss | (324,202) | (186,313) | (93,943) | (98,867) | (88,916) | |
| Revenues | 94,588) | 70,428) | 55,828) | 26,868) | 31,501) | |
| Profitability Ratio | ||||||
| Operating profit margin1 | -342.75% | -264.54% | -168.27% | -367.97% | -282.26% | |
| Benchmarks | ||||||
| Operating Profit Margin, Competitors2 | ||||||
| AbbVie Inc. | 31.21% | 31.89% | 24.81% | 39.03% | — | |
| Amgen Inc. | 38.57% | 31.44% | 37.70% | 43.57% | — | |
| Bristol-Myers Squibb Co. | 17.96% | 15.91% | -21.60% | 22.62% | — | |
| Danaher Corp. | 27.61% | 25.35% | 18.99% | 18.25% | — | |
| Eli Lilly & Co. | 24.97% | 22.45% | 24.69% | 22.29% | — | |
| Gilead Sciences Inc. | 27.17% | 36.72% | 16.72% | 19.38% | — | |
| Johnson & Johnson | 24.63% | 24.95% | 23.60% | 24.15% | — | |
| Merck & Co. Inc. | 30.27% | 25.74% | 16.47% | 24.77% | — | |
| Pfizer Inc. | 34.83% | 23.91% | 19.47% | 25.46% | — | |
| Regeneron Pharmaceuticals Inc. | 38.93% | 55.67% | 42.09% | 28.10% | — | |
| Thermo Fisher Scientific Inc. | 18.69% | 25.57% | 24.19% | 17.99% | — | |
| Zoetis Inc. | 36.10% | 35.49% | 33.62% | 31.42% | — | |
| Operating Profit Margin, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 28.27% | 26.84% | 18.54% | 25.93% | — | |
| Operating Profit Margin, Industry | ||||||
| Health Care | 13.22% | 13.18% | 10.47% | 12.45% | — | |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31).
1 2022 Calculation
Operating profit margin = 100 × Operating loss ÷ Revenues
= 100 × -324,202 ÷ 94,588 = -342.75%
2 Click competitor name to see calculations.
| Profitability ratio | Description | The company |
|---|---|---|
| Operating profit margin | A profitability ratio calculated as operating income divided by revenue. | Cytokinetics Inc. operating profit margin ratio deteriorated from 2020 to 2021 and from 2021 to 2022. |
Net Profit Margin
Cytokinetics Inc., net profit margin calculation, comparison to benchmarks
| Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | ||
|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||
| Net loss | (388,955) | (215,314) | (127,290) | (121,692) | (106,289) | |
| Revenues | 94,588) | 70,428) | 55,828) | 26,868) | 31,501) | |
| Profitability Ratio | ||||||
| Net profit margin1 | -411.21% | -305.72% | -228.00% | -452.93% | -337.41% | |
| Benchmarks | ||||||
| Net Profit Margin, Competitors2 | ||||||
| AbbVie Inc. | 20.39% | 20.54% | 10.08% | 23.69% | — | |
| Amgen Inc. | 26.42% | 24.25% | 29.97% | 35.32% | — | |
| Bristol-Myers Squibb Co. | 13.71% | 15.08% | -21.20% | 13.15% | — | |
| Danaher Corp. | 22.91% | 21.84% | 16.36% | 16.80% | — | |
| Eli Lilly & Co. | 21.88% | 19.71% | 25.24% | 37.27% | — | |
| Gilead Sciences Inc. | 17.02% | 23.05% | 0.51% | 24.35% | — | |
| Johnson & Johnson | 18.90% | 22.26% | 17.82% | 18.42% | — | |
| Merck & Co. Inc. | 24.49% | 26.79% | 14.72% | 21.01% | — | |
| Pfizer Inc. | 31.27% | 27.04% | 22.95% | 31.45% | — | |
| Regeneron Pharmaceuticals Inc. | 35.64% | 50.25% | 41.35% | 26.91% | — | |
| Thermo Fisher Scientific Inc. | 15.47% | 19.70% | 19.79% | 14.47% | — | |
| Zoetis Inc. | 26.16% | 26.20% | 24.54% | 23.96% | — | |
| Net Profit Margin, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 22.40% | 23.35% | 13.81% | 23.18% | — | |
| Net Profit Margin, Industry | ||||||
| Health Care | 10.25% | 10.89% | 7.78% | 10.20% | — | |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31).
1 2022 Calculation
Net profit margin = 100 × Net loss ÷ Revenues
= 100 × -388,955 ÷ 94,588 = -411.21%
2 Click competitor name to see calculations.
| Profitability ratio | Description | The company |
|---|---|---|
| Net profit margin | An indicator of profitability, calculated as net income divided by revenue. | Cytokinetics Inc. net profit margin ratio deteriorated from 2020 to 2021 and from 2021 to 2022. |
Return on Equity (ROE)
Cytokinetics Inc., ROE calculation, comparison to benchmarks
| Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | ||
|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||
| Net loss | (388,955) | (215,314) | (127,290) | (121,692) | (106,289) | |
| Stockholders’ equity (deficit) | (107,900) | 243,863) | 113,383) | (10,937) | 25,934) | |
| Profitability Ratio | ||||||
| ROE1 | — | -88.29% | -112.27% | — | -409.84% | |
| Benchmarks | ||||||
| ROE, Competitors2 | ||||||
| AbbVie Inc. | 68.60% | 74.91% | 35.30% | — | — | |
| Amgen Inc. | 178.97% | 87.96% | 77.20% | 81.07% | — | |
| Bristol-Myers Squibb Co. | 20.37% | 19.46% | -23.84% | 6.66% | — | |
| Danaher Corp. | 14.39% | 14.24% | 9.17% | 9.94% | — | |
| Eli Lilly & Co. | 58.64% | 62.16% | 109.79% | 319.09% | — | |
| Gilead Sciences Inc. | 21.62% | 29.55% | 0.68% | 23.91% | — | |
| Johnson & Johnson | 23.36% | 28.20% | 23.25% | 25.42% | — | |
| Merck & Co. Inc. | 31.57% | 34.17% | 27.91% | 37.99% | — | |
| Pfizer Inc. | 32.79% | 28.47% | 15.21% | 25.77% | — | |
| Regeneron Pharmaceuticals Inc. | 19.14% | 43.03% | 31.86% | 19.08% | — | |
| Thermo Fisher Scientific Inc. | 15.80% | 18.94% | 18.47% | 12.45% | — | |
| Zoetis Inc. | 47.99% | 44.84% | 43.46% | 55.39% | — | |
| ROE, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 28.34% | 30.10% | 17.15% | 28.09% | — | |
| ROE, Industry | ||||||
| Health Care | 22.50% | 23.00% | 16.15% | 21.18% | — | |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31).
1 2022 Calculation
ROE = 100 × Net loss ÷ Stockholders’ equity (deficit)
= 100 × -388,955 ÷ -107,900 = —
2 Click competitor name to see calculations.
Return on Assets (ROA)
Cytokinetics Inc., ROA calculation, comparison to benchmarks
| Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | ||
|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||
| Net loss | (388,955) | (215,314) | (127,290) | (121,692) | (106,289) | |
| Total assets | 1,014,775) | 841,319) | 533,803) | 289,814) | 211,178) | |
| Profitability Ratio | ||||||
| ROA1 | -38.33% | -25.59% | -23.85% | -41.99% | -50.33% | |
| Benchmarks | ||||||
| ROA, Competitors2 | ||||||
| AbbVie Inc. | 8.53% | 7.88% | 3.07% | 8.84% | — | |
| Amgen Inc. | 10.06% | 9.63% | 11.54% | 13.13% | — | |
| Bristol-Myers Squibb Co. | 6.53% | 6.40% | -7.61% | 2.65% | — | |
| Danaher Corp. | 8.55% | 7.73% | 4.79% | 4.85% | — | |
| Eli Lilly & Co. | 12.62% | 11.44% | 13.28% | 21.17% | — | |
| Gilead Sciences Inc. | 7.27% | 9.16% | 0.18% | 8.74% | — | |
| Johnson & Johnson | 9.57% | 11.47% | 8.41% | 9.59% | — | |
| Merck & Co. Inc. | 13.30% | 12.35% | 7.72% | 11.66% | — | |
| Pfizer Inc. | 15.91% | 12.11% | 6.23% | 9.72% | — | |
| Regeneron Pharmaceuticals Inc. | 14.85% | 31.75% | 20.47% | 14.29% | — | |
| Thermo Fisher Scientific Inc. | 7.15% | 8.12% | 9.23% | 6.33% | — | |
| Zoetis Inc. | 14.16% | 14.65% | 12.04% | 12.99% | — | |
| ROA, Sector | ||||||
| Pharmaceuticals, Biotechnology & Life Sciences | 10.59% | 10.39% | 5.34% | 9.02% | — | |
| ROA, Industry | ||||||
| Health Care | 8.34% | 8.24% | 5.46% | 7.22% | — | |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31).
1 2022 Calculation
ROA = 100 × Net loss ÷ Total assets
= 100 × -388,955 ÷ 1,014,775 = -38.33%
2 Click competitor name to see calculations.
| Profitability ratio | Description | The company |
|---|---|---|
| ROA | A profitability ratio calculated as net income divided by total assets. | Cytokinetics Inc. ROA deteriorated from 2020 to 2021 and from 2021 to 2022. |